THE RESEARCH
Peptide research and clinical studies behind P11.
Below are some of the published peer-reviewed studies supporting the efficacy of each active peptide in P11. All citations are for individual ingredients. P11 as a finished formula has not undergone independent clinical testing.
Copper Tripeptide-1 (GHK-Cu)
Effects of GHK-Cu on MMP and TIMP Expression, Collagen and Elastin Production, and Facial Wrinkle Parameters — Badenhorst et al. (2016), Journal of Aging Science
View StudyRole of Topical Peptides in Preventing or Treating Aged Skin — Gorouhi & Maibach (2009), International Journal of Cosmetic Science
View StudyAcetyl Octapeptide-3
Role of Topical Peptides in Preventing or Treating Aged Skin — Gorouhi & Maibach (2009), International Journal of Cosmetic Science
View StudyCosmeceutical Peptides in the Framework of Sustainable Wellness Economy — Errante et al. (2020), Frontiers in Chemistry
View StudyAcetyl Hexapeptide-8
A Synthetic Hexapeptide (Argireline) with Antiwrinkle Activity — Blanes-Mira et al. (2002), International Journal of Cosmetic Science
View StudyThe Anti-Wrinkle Efficacy of Argireline — Wang et al. (2009), Journal of Cosmetic and Laser Therapy
View StudyTripeptide-10 Citrulline
The Efficacy Study of the Combination of Tripeptide-10-Citrulline and Acetyl Hexapeptide-3 — Raikou et al. (2017), Journal of Cosmetic Dermatology
View StudyA New Decorin-Like Tetrapeptide for Optimal Organization of Collagen Fibres — Puig et al. (2008), International Journal of Cosmetic Science
View StudyPalmitoyl Tripeptide-38
A serum containing vitamins C & E and a matrix-repair tripeptide reduces facial signs of aging as evidenced by Primos analysis and frequently repeated auto-perception — Lintner et al. (2020), Journal of Cosmetic Dermatology
View StudyA Face Serum Containing Palmitoyl Tripeptide-38 Improves Skin Quality — West et al. (2021), Journal of Cosmetics, Dermatological Sciences and Applications
View StudyHydrolyzed Vegetable / Wheat / Soy Protein Blend
Synergistic Action of a Triple Peptide Complex on an Essential Extracellular Matrix Protein Exhibits Significant Anti-Aging Benefits — Byrne et al. (2010), Journal of Cosmetic Dermatology
View StudyThe Efficacy Study of the Combination of Tripeptide-10-Citrulline and Acetyl Hexapeptide-3 — Raikou et al. (2017), Journal of Cosmetic Dermatology
View StudyPalmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7
Clinical Evidence of the Efficacy and Safety of a New Multi-Peptide Anti-Aging Topical Eye Serum — Li et al. (2023), Journal of Cosmetic Dermatology
View StudyA Serum Containing Vitamins C & E and a Matrix-Repair Tripeptide Reduces Facial Signs of Aging — Lintner et al. (2020), Journal of Cosmetic Dermatology
View StudyTetrapeptide-21
Bioactive Tetrapeptide GEKG Boosts Extracellular Matrix Formation: In Vitro and In Vivo Molecular and Clinical Proof — Farwick et al. (2011), Experimental Dermatology
View StudyElastin-Derived Peptide Hydrogels for Sustained Dermal Delivery of Tetrapeptide-21 — ScienceDirect (2025)
View StudyTripeptide-29
Effect of a Topical Collagen Tripeptide on Antiaging and Inhibition of Glycation of the Skin: A Pilot Study — Choi et al. (2022), International Journal of Molecular Sciences
View StudyCollagen-Derived Dipeptide, Proline-Hydroxyproline, Stimulates Cell Proliferation and Hyaluronic Acid Synthesis in Cultured Human Dermal Fibroblasts — Ohara et al. (2010), Journal of Dermatological Science
View StudyAcetyl Hexapeptide-30
Supported by manufacturer clinical data. Independent peer-reviewed trials are limited for this ingredient.
Inyline Peptide Solution — Lubrizol Life Science Technical Dossier (Manufacturer Clinical Data)
View StudyAcetyl Tetrapeptide-40
Supported by manufacturer clinical data. Independent peer-reviewed trials are limited for this ingredient.
Uplevity Peptide Solution — Lubrizol Life Science Technical Dossier (Manufacturer Clinical Data)
View StudyAll linked studies are published research on individual peptide ingredients and do not constitute clinical evidence for P11 as a finished formula. P11 has not undergone independent third-party clinical testing. Individual results may vary.