THE RESEARCH

Peptide research and clinical studies behind P11.

Below are some of the published peer-reviewed studies supporting the efficacy of each active peptide in P11. All citations are for individual ingredients. P11 as a finished formula has not undergone independent clinical testing.

GHK-Cu

Copper Tripeptide-1 (GHK-Cu)

Effects of GHK-Cu on MMP and TIMP Expression, Collagen and Elastin Production, and Facial Wrinkle Parameters — Badenhorst et al. (2016), Journal of Aging Science

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Role of Topical Peptides in Preventing or Treating Aged Skin — Gorouhi & Maibach (2009), International Journal of Cosmetic Science

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SNAP-8

Acetyl Octapeptide-3

Role of Topical Peptides in Preventing or Treating Aged Skin — Gorouhi & Maibach (2009), International Journal of Cosmetic Science

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Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy — Errante et al. (2020), Frontiers in Chemistry

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Neuropeptide

Acetyl Hexapeptide-8

A Synthetic Hexapeptide (Argireline) with Antiwrinkle Activity — Blanes-Mira et al. (2002), International Journal of Cosmetic Science

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The Anti-Wrinkle Efficacy of Argireline — Wang et al. (2009), Journal of Cosmetic and Laser Therapy

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Collagen Organizer

Tripeptide-10 Citrulline

The Efficacy Study of the Combination of Tripeptide-10-Citrulline and Acetyl Hexapeptide-3 — Raikou et al. (2017), Journal of Cosmetic Dermatology

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A New Decorin-Like Tetrapeptide for Optimal Organization of Collagen Fibres — Puig et al. (2008), International Journal of Cosmetic Science

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Matrix Peptide

Palmitoyl Tripeptide-38

A serum containing vitamins C & E and a matrix-repair tripeptide reduces facial signs of aging as evidenced by Primos analysis and frequently repeated auto-perception — Lintner et al. (2020), Journal of Cosmetic Dermatology

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A Face Serum Containing Palmitoyl Tripeptide-38 Improves Skin Quality — West et al. (2021), Journal of Cosmetics, Dermatological Sciences and Applications

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Peptide Blend

Hydrolyzed Vegetable / Wheat / Soy Protein Blend

Synergistic Action of a Triple Peptide Complex on an Essential Extracellular Matrix Protein Exhibits Significant Anti-Aging Benefits — Byrne et al. (2010), Journal of Cosmetic Dermatology

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The Efficacy Study of the Combination of Tripeptide-10-Citrulline and Acetyl Hexapeptide-3 — Raikou et al. (2017), Journal of Cosmetic Dermatology

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Signal Peptide

Palmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7

Clinical Evidence of the Efficacy and Safety of a New Multi-Peptide Anti-Aging Topical Eye Serum — Li et al. (2023), Journal of Cosmetic Dermatology

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A Serum Containing Vitamins C & E and a Matrix-Repair Tripeptide Reduces Facial Signs of Aging — Lintner et al. (2020), Journal of Cosmetic Dermatology

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ECM Peptide

Tetrapeptide-21

Bioactive Tetrapeptide GEKG Boosts Extracellular Matrix Formation: In Vitro and In Vivo Molecular and Clinical Proof — Farwick et al. (2011), Experimental Dermatology

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Elastin-Derived Peptide Hydrogels for Sustained Dermal Delivery of Tetrapeptide-21 — ScienceDirect (2025)

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Collagen Tripeptide

Tripeptide-29

Effect of a Topical Collagen Tripeptide on Antiaging and Inhibition of Glycation of the Skin: A Pilot Study — Choi et al. (2022), International Journal of Molecular Sciences

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Collagen-Derived Dipeptide, Proline-Hydroxyproline, Stimulates Cell Proliferation and Hyaluronic Acid Synthesis in Cultured Human Dermal Fibroblasts — Ohara et al. (2010), Journal of Dermatological Science

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Neuropeptide

Acetyl Hexapeptide-30

Supported by manufacturer clinical data. Independent peer-reviewed trials are limited for this ingredient.

Inyline Peptide Solution — Lubrizol Life Science Technical Dossier (Manufacturer Clinical Data)

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Lifting Peptide

Acetyl Tetrapeptide-40

Supported by manufacturer clinical data. Independent peer-reviewed trials are limited for this ingredient.

Uplevity Peptide Solution — Lubrizol Life Science Technical Dossier (Manufacturer Clinical Data)

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All linked studies are published research on individual peptide ingredients and do not constitute clinical evidence for P11 as a finished formula. P11 has not undergone independent third-party clinical testing. Individual results may vary.